Publications

Page


Book Chapters

McConnell, M.J., and F.H. Gage.  (2013).  Neuronal Genomic and Epigenomic Diversity.  In Epigenetic Regulation in the Nervous System: Basic Mechanisms and Clinical Impact.  D. Sweatt, M. Meaney, S. Akbarian, and E. Nestler, Editors.  Elsevier:  pp. 281 – 298.

Sartore, R.C., Campos, P.B., McConnell, M.J., and S.K. Rehen.  (2010).  Aneuploidy in Embryonic Stem Cells.  In Perspectives in Stem Cells.  H. Ullrich, Editor.  Springer: Netherlands.  pp. 73 – 86.

Publications
McConnell, M.J., Lindberg, M.R., Brennand, K.J., Piper, J.C., Voet, T., Cowing-Zitron, C., Schumilina, S., Lasken, R.S., Vermeesch, J. R., Hall, I.M., and F.H. Gage. (2013).  Mosaic copy number variation in human neurons.  Science. 342(6148):632-637.

Grindberg, R.V. Yee-Greenbaum,J.*, McConnell, M.J.*,Novotny, M., O’ Shaughnessy, A., Lambert, G., Araúzo-Bravo, M.J., Lee, J., Fishmand, M., Robbins, G., Lin, X., Galbraith, D., Gage, F.H., and R.S. Lasken. (2013). RNA-seq from single nuclei.  Proceedings of the National Academy of Sciences USA.  110(49):19802-19807.

Singer, T., McConnell, M.J., Marchetto, M.C., Coufal, N.G., and F.H. Gage.  (2010).  LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?  Trends in Neurosciences.  33(8):345-54.

MacMillan, H.R. and M.J. McConnell. (2010). Seeing beyond the average cell: branching process models of cell proliferation, differentiation, and death during mouse brain development. Theory in Biosciences. Sept. 8.

Datwani, A., McConnell, M.J., Kanold, P.O., Micheva, K.D., Busse, B., Shamloo, M., Smith, S.J., and C.J. Shatz. (2009). Classical MHCI molecules regulate retinogeniculate refinement and limit ocular dominance plasticity. Neuron. 64:463-470.

McConnell, M.J.*, Huang. Y.H.*, Datwani, A. and C.J. Shatz. (2009). H2-Kb and H2-Db regulate cerebellar long term depression and limit motor learning. Proceedings of the National Academy of Sciences USA. 106(16): 6784-6789.

McConnell, M.J., MacMillan, H.R., and J. Chun. (2009). Mathematical modeling supports substantial mouse neural progenitor cell death. Neural Development. 4: 28.

Kingsbury, M.A., Friedman, B., McConnell, M.J., Rehen, S.K., Yang, A.H., Kaushal, D., and J. Chun. (2005). Aneuploid neurons are functionally active and integrated into brain circuitry. Proceedings of the National Academy of Sciences USA. 102(17): 6143 – 6147.

Rehen, S.K.*, Yung, Y.C.*, McCreight, M.P., Kaushal, D., Yang, A.H., Almeida, B.S.V., Kingsbury, M.A., Cabral, K.M.S., McConnell, M.J., Anliker,B., Fontanoz, M., and J. Chun. (2005). Constitutional aneuploidy in the normal human brain. The Journal of Neuroscience. 25(9): 2176 – 2180.

McConnell, M.J., Kaushal, D., Yang, A.H., Kingsbury, M.A., Rehen, S.K., Treuner, K., Helton, R., Annas, E., Chun, J., and C. Barlow. (2004). Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex. The Journal of Neuroscience. 24(37): 8090 – 8096.

Yang, A.H., Kaushal, D., Kingsbury, M.A., Rehen, S.K., McConnell, M.J., and J. Chun. (2003). Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells. The Journal of Neuroscience. 23(32): 10454 – 10462.

Kaushal, D., Contos, J.J.A., Treuner, K. Yang, A.H., Kingsbury, M.A., Rehen, S.K., McConnell, M.J., Okabe, M., Barlow, C., and J. Chun. (2003). Alteration of gene expression by chromosome loss in the postnatal mouse brain. The Journal of Neuroscience. 23(13): 5599 – 5606.

Zhao, X., Ueba, T., Christie, B., Barkho, B., McConnell, M.J., Nakashima, K., Lein, E.S., Eadie, B., Willhoite, A.R., Muotri, A.R., Summers, R.G., Chun, J., Lee, K.-F., and F.H. Gage. (2003). Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences USA. 100(11): 6777 – 6782.

MacMillan, H.R., McConnell, M.J., and K. Tai. (2002). Biological system of analysis of systems math. WSEAS Conference on Applied Mathematics and Computer Science Proceedings, Rio de Janeiro, Brazil.

Rehen, S.K., McConnell, M.J., Kaushal, D., Kingsbury, M.A., Yang, A.H., and J. Chun. (2002). Genetic mosaicism in the brain: a new paradigm for neuronal diversity. Directions in Science. 1: 53 – 55.

Rehen, S.K.,* McConnell, M.J.,* Kaushal, D.,* Kingsbury, M.A., Yang, A.H., and J. Chun. (2001). Chromosomal variation in neurons of the developing and adult mammalian nervous system. Proceedings of the National Academy of Sciences USA. 98(23): 13361 -13366.

Ottilie, S., Diaz, J.-L., Chang, J., Wilson, G., Tuffo, K.M., Weeks, S., McConnell, M., Wang, Y., Oltersdorf, T., and L.C. Fritz. (1997). Structural and functional complementation of an inactive Bcl-2 mutant by Bax truncation. The Journal of Biological Chemistry. 272(27): 16955 -16961.

Diaz, J.-L., Horne, W., McConnell, M., Wilson, G., Weeks, S., Garcia, T., Oltersdorf, T., and L.C. Fritz. (1997). A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members. The Journal of Biological Chemistry. 272(17): 11350 -11355.

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